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R&D Systems™ PARP Enzyme High Specific Activity

Purified from E. coli containing a recombinant plasmid harboring the human PARP gene

Brand:  R&D Systems™ 4668-100-01

Code : Z1

Additional Details : Weight : 0.00010kg

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Product Code. 13445024

  • £354.27 / 100µL

Estimated Shipment date
from Supplier 23-12-2019

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PARP [Poly(ADP-ribose) Polymerase], also known as ADPRT and PPOL, is a 118kDa enzyme that uses NAD as a substrate to catalyze the covalent transfer of ADP-ribose to a variety of nuclear protein acceptors. ADP ribosyltransferase is required for cellular repair, and PARP expression is induced by single-strand breaks in DNA. PARP is proteolytically cleaved by Caspase-3 into two fragments of 89 and 24kDa in one of the hallmark events of apoptosis.

  • One unit of PARP incorporates 10femtomoles of NAD onto immobilized histones in 30 minutes
  • High specific activity PARP is provided at 10 units/μL



Poly [ADP-ribose] Polymerase Enzyme High Specific Activity
Store at -20° C in a manual defrost freezer. For long-term storage, freeze in working aliquots at -80° C. Avoid freeze-thaw cycles.