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R&D Systems™ Human TRAIL/TNFSF10 Recombinant Protein

Brand:  R&D Systems™ 375-TL-010/CF

Code : Z1

Additional Details : Weight : 0.00010kg

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Product Code. 13463564

  • £349.81 / 10µg


Estimated Shipment
03-04-2019
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Description

Description

Measured in a cytotoxicity assay using L-929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D. Matthews, N. and M.L. Neale (1987) in Lymphokines and Interferons, A Practical Approach. Clemens, M.J. et al. (eds): IRL Press. 221. The ED 50 for this effect is 4-12 ng/mL. The apoptotic effect of soluble trimeric rhTRAIL can be enhanced by oligimerization of the soluble rhTRAIL through the use of a cross-linking antibody Mouse Anti-polyHistidine Monoclonal Antibody (Catalog # MAB050 ). The ED 50 for this effect is 1-4 ng/mL. Note: This is one of multiple forms available for this protein. Check R&D Systems' website, www.RnDSystems.com, for a complete listing of the variants.
Specifications

Specifications

Lyophilized from a 0.2μm filtered solution in PBS.
21 kDa (monomer)
97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Human
Noncovalently-linked homotrimer and disulfide-linked homodimer
Yes
8743
TRAIL/TNFSF10
10μg
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70° C as supplied. 1 month, 2 to 8° C under sterile conditions after reconstitution. 3 months, -70° C under sterile conditions after reconstitution.
Unlabeled
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