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R&D Systems™ Recombinant Human GDNF Protein
Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility. Applications: Bioactivity, Binding Activity
POA
Specifications
| Gene ID (Entrez) | 2668 |
|---|---|
| Molecular Weight (g/mol) | 11.6 kDa (monomer) |
| Name | GDNF |
| Source | Mouse myeloma cell line,NS0-derived human GDNF protein Arg109-Ile211 |
| Storage Requirements | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70° C as supplied. 1 month, 2 to 8° C under sterile conditions after reconstitution. 3 months, -20 to -70° C under sterile conditions after reconstitution. |
Description
Measured in a cell proliferation assay using SH-SY5Y human neuroblastoma cells. The ED50 for this effect is 2-12 ng/mL in the presence of Recombinant Human GFR alpha-1/GDNF R alpha-1 Fc Chimera (Catalog # 714-GR ). Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human GFR alpha-1/GDNF R alpha-1 Fc Chimera (Catalog # 714-GR ) at 1 μg/mL can bind Recombinant Human GDNF with an apparent Kd <1 nM.Specifications
| 2668 | |
| GDNF | |
| Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70° C as supplied. 1 month, 2 to 8° C under sterile conditions after reconstitution. 3 months, -20 to -70° C under sterile conditions after reconstitution. | |
| Unconjugated | |
| 97%, by SDS-PAGE under reducing conditions and visualized by silver stain. |
| 11.6 kDa (monomer) | |
| Mouse myeloma cell line,NS0-derived human GDNF protein Arg109-Ile211 | |
| Disulfide-linked homodimer | |
| Recombinant |