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PX 12, Tocris Bioscience™

Thioredoxin-1 inhibitor

Brand:  Tocris (Bio-Techne) 295450

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 50mg

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Product Code. 13462124

  • £427.72 / 50mg


Estimated Shipment
03-09-2018
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Description

Description

Thioredoxin-1 (Trx-1) inhibitor; irreversibly inactivates Trx-1 as a substrate for reduction by thioredoxin reductase (TR); competitively inhibits the reduction of Trx-1 by TR (Ki = 30.8μM). Attenuates expression of HIF-1α, VEGF and iNOS (IC50 values are 7.2, 10.4 and 18.1μM respectively). Exhibits antitumor activity; directly inhibits tubulin in vitro and decreases tumor microvessel density in vivo.
Specifications

Chemical Identifiers

141400-58-0
188.307
2-[(1-Methylpropyl)dithio]-1H-imidazole
C7H12N2S2
BPBPYQWMFCTCNG-UHFFFAOYSA-N
219104

Specifications

PX 12
141400-58-0
C7H12N2S2
BPBPYQWMFCTCNG-UHFFFAOYSA-N
2-(butan-2-yldisulfanyl)-1H-imidazole
219104
50mg
>99%
2-[(1-Methylpropyl)dithio]-1H-imidazole
CCC(C)SSC1=NC=CN1
188.307
188.31
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