missing translation for 'onlineSavingsMsg'
Learn More

Purvalanol B, Tocris Bioscience™

Selective cdk inhibitor; potently inhibits cdk1, cdk2 and cdk5

Brand:  Tocris (Bio-Techne) 158110

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 10mg

 View more versions of this product

Product Code. 13469713

  • £227.85 / 10mg

Estimated Shipment date
from Supplier 03-04-2020

Please to purchase this item. Need a web account? Register with us today!


Description

Description

Cyclin-dependent kinase (cdk) inhibitor (reported IC50 values are 6 nM for cdk1 and cdk5, and 6 - 9 nM for cdk2, depending on binding partner). Selective over a range of other protein kinases (IC50 >10,000 nM). Shown to have antiproliferative properties, mediated by ERK1 and ERK2.
Specifications

Chemical Identifiers

212844-54-7
432.909
purvalanol b, purvalanol, purvalanol b ng-95, purvalanol b ng 95, 2r-2-6-3-chloro-4-carboxyphenyl amino-9-1-methylethyl-9h-purin-2-yl amino-3-methyl-1-butanol, chembl23254, r-2-chloro-4-2-1-hydroxy-3-methylbutan-2-yl amino-9-isopropyl-9h-purin-6-yl amino benzoic acid, 2-chloro-4-2-2r-1-hydroxy-3-methylbutan-2-yl amino-9-propan-2-ylpurin-6-yl amino benzoic acid, r-2-chloro-4-2-1-hydroxy-3-methylbutan-2-ylamino-9-isopropyl-9h-purin-6-ylamino benzoic acid, pvb
CHEBI:49840
CC(C)C(CO)NC1=NC2=C(C(=N1)NC3=CC(=C(C=C3)C(=O)O)Cl)N=CN2C(C)C
C20H25ClN6O3
ZKDXRFMOHZVXSG-HNNXBMFYSA-N
448991
2-chloro-4-[[2-[[(2R)-1-hydroxy-3-methylbutan-2-yl]amino]-9-propan-2-ylpurin-6-yl]amino]benzoic acid

Specifications

10mg
212844-54-7
purvalanol b, purvalanol, purvalanol b ng-95, purvalanol b ng 95, 2r-2-6-3-chloro-4-carboxyphenyl amino-9-1-methylethyl-9h-purin-2-yl amino-3-methyl-1-butanol, chembl23254, r-2-chloro-4-2-1-hydroxy-3-methylbutan-2-yl amino-9-isopropyl-9h-purin-6-yl amino benzoic acid, 2-chloro-4-2-2r-1-hydroxy-3-methylbutan-2-yl amino-9-propan-2-ylpurin-6-yl amino benzoic acid, r-2-chloro-4-2-1-hydroxy-3-methylbutan-2-ylamino-9-isopropyl-9h-purin-6-ylamino benzoic acid, pvb
CC(C)C(CO)NC1=NC2=C(C(=N1)NC3=CC(=C(C=C3)C(=O)O)Cl)N=CN2C(C)C
432.909
CHEBI:49840
>99%
Purvalanol B
C20H25ClN6O3
ZKDXRFMOHZVXSG-HNNXBMFYSA-N
2-chloro-4-[[2-[[(2R)-1-hydroxy-3-methylbutan-2-yl]amino]-9-propan-2-ylpurin-6-yl]amino]benzoic acid
448991
432.91
Videos
Documents