missing translation for 'onlineSavingsMsg'
Learn More

PP 121, Tocris Bioscience™

Dual kinase inhibitor; inhibits PI 3-K family kinases

Brand:  Tocris (Bio-Techne) 389450

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 50mg

 View more versions of this product

Product Code. 13443774

  • £645.33 / 50mg

Estimated Shipment date
from Supplier 28-10-2019

Please to purchase this item. Need a web account? Register with us today!


Description

Description

Dual inhibitor of receptor tyrosine kinases (RTKs) (IC50 < 0.02μM for Abl, Src, VEGFR-2 and PDGFR) and PI 3-K family kinases (IC50 < 0.06μM for p110α, DNA-PK and mTOR). Exhibits no significant effect on receptor serine/threonine kinases (RSTKs). Blocks the proliferation of tumor cells by direct inhibition of PI 3-K, mTOR, Src and the VEGF receptor.
Specifications

Chemical Identifiers

1092788-83-4
319.372
1-cyclopentyl-3-1h-pyrrolo 2,3-b pyridin-5-yl-1h-pyrazolo 3,4-d pyrimidin-4-amine, 1-cyclopentyl-3-1h-pyrrolo 2,3-b pyridin-5-yl pyrazolo 3,4-d pyrimidin-4-amine, 1h-pyrazolo 3,4-d pyrimidin-4-amine, 1-cyclopentyl-3-1h-pyrrolo 2,3-b pyridin-5-yl, ks1, kinome_2001, d03ehm, pp hplc
CHEBI:50915
C1CCC(C1)N2C3=C(C(=N2)C4=CN=C5C(=C4)C=CN5)C(=NC=N3)N
C17H17N7
NVRXTLZYXZNATH-UHFFFAOYSA-N
24905142
1-cyclopentyl-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)pyrazolo[3,4-d]pyrimidin-4-amine

Specifications

50mg
1092788-83-4
1-cyclopentyl-3-1h-pyrrolo 2,3-b pyridin-5-yl-1h-pyrazolo 3,4-d pyrimidin-4-amine, 1-cyclopentyl-3-1h-pyrrolo 2,3-b pyridin-5-yl pyrazolo 3,4-d pyrimidin-4-amine, 1h-pyrazolo 3,4-d pyrimidin-4-amine, 1-cyclopentyl-3-1h-pyrrolo 2,3-b pyridin-5-yl, ks1, kinome_2001, d03ehm, pp hplc
C1CCC(C1)N2C3=C(C(=N2)C4=CN=C5C(=C4)C=CN5)C(=NC=N3)N
319.372
CHEBI:50915
>99%
PP 121
C17H17N7
NVRXTLZYXZNATH-UHFFFAOYSA-N
1-cyclopentyl-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)pyrazolo[3,4-d]pyrimidin-4-amine
24905142
319.36
Videos
Documents