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Poly(I:C), Tocris Bioscience™

TLR3 agonist

Brand:  Tocris (Bio-Techne) 428750

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 50mg

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Product Code. 13434494

  • £361.62 / 50mg

Estimated Shipment date
from Supplier 21-11-2019

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Description

Description

Synthetic double-stranded RNA (dsRNA); Toll-like receptor 3 (TLR3) agonist. Aids generation of stable, mature dendritic cells in combination with TLR8 agonist CL 075 . Transfection into NIT-1 β cells induces β-cell apoptosis. Immunostimulant.

To prevent denaturation, this product should be reconstituted in solutions with physiological salt concentrations.

Specifications

Chemical Identifiers

24939-03-5
671.406
poly i:c
[(2R,3S,4S,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate;[(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-3H-purin-9-yl)oxolan-2-yl]methyl dihydrogen phosphate
C19H27N7O16P2
ACEVNMQDUCOKHT-YJZUVTEISA-N
124080975
C1=CN(C(=O)N=C1N)C2C(C(C(O2)COP(=O)(O)O)O)O.C1=NC(=O)C2=C(N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)O)O)O

Specifications

50mg
24939-03-5
poly i:c
C1=CN(C(=O)N=C1N)C2C(C(C(O2)COP(=O)(O)O)O)O.C1=NC(=O)C2=C(N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)O)O)O
671.406
>98%
Poly(I:C)
C19H27N7O16P2
ACEVNMQDUCOKHT-YJZUVTEISA-N
[(2R,3S,4S,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate;[(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-3H-purin-9-yl)oxolan-2-yl]methyl dihydrogen phosphate
124080975
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