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Pokemon (LRF) Armenian Hamster anti-Human, eFluor 660, Clone: 13E9, eBioscience™

Armenian Hamster Monoclonal Antibody

Brand:  Affymetrix eBioscience 50-3309-82

Code : NEW

Additional Details : Weight : 0.09500kg

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Product Code. 15599926

This item has been discontinued and is no longer available. View the product for possible alternatives or contact our Product Support team on 01509 555888 for assistance

Disclaimers:

For Research Use Only.


Specifications

Description

This monoclonal antibody reacts with human Leukemia/lymphoma-related factor (LRF). This 65kDa protein is also known as POKEMON, FBI-1, and Zbtb7a. LRF is a member of the POK family of transcriptional repressors, and is expressed in hematopoietic stem cells, T and B lymphocytes, macrophages, and erythroid cells. This protein is also highly expressed in human non-Hodgkin’s lymphoma tissues and diffuse large B-cell lymphomas, demonstrating its prominent role in oncogenic transformation. Studies have demonstrated that LRF is also involved in B cell lineage commitment and development by opposing Notch signaling. Moreover, LRF is critical for erythroid terminal differentiation in the bone marrow by inhibiting Bim-mediated apoptosis. Finally, LRF interacts with Bcl-6 in germinal center B cells.
Description & Specifications

Specifications

Pokemon (LRF)
1.30E+10
eFluor 660
Conjugated
Armenian Hamster
100μg
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Immunohistochemistry (Formalin/Paraffin)
0.2mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Leukemia/lymphoma-related factor
IgG
RUO
Primary
Human