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Pokemon (LRF) Armenian Hamster anti-Human, eFluor 660, Clone: 13E9, eBioscience™

Armenian Hamster Monoclonal Antibody

Brand:  Affymetrix eBioscience 50-3309-82

Code : NEW

Additional Details : Weight : 0.09500kg

Product Code. 15599926

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Description

Description

This monoclonal antibody reacts with human Leukemia/lymphoma-related factor (LRF). This 65kDa protein is also known as POKEMON, FBI-1, and Zbtb7a. LRF is a member of the POK family of transcriptional repressors, and is expressed in hematopoietic stem cells, T and B lymphocytes, macrophages, and erythroid cells. This protein is also highly expressed in human non-Hodgkin’s lymphoma tissues and diffuse large B-cell lymphomas, demonstrating its prominent role in oncogenic transformation. Studies have demonstrated that LRF is also involved in B cell lineage commitment and development by opposing Notch signaling. Moreover, LRF is critical for erythroid terminal differentiation in the bone marrow by inhibiting Bim-mediated apoptosis. Finally, LRF interacts with Bcl-6 in germinal center B cells.
Specifications

Specifications

Pokemon (LRF)
1.30E+10
eFluor 660
Conjugated
Armenian Hamster
100μg
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Immunocytochemistry, Immunohistochemistry
0.2mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Leukemia/lymphoma-related factor
IgG
RUO
Primary
Human
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For Research Use Only.