Pokemon (LRF) Armenian Hamster anti-Human, Clone: 13E9, eBioscience™

Armenian Hamster Monoclonal Antibody

Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-3309-80


UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg

Disclaimers: For Research Use Only.

Product Code. 15237347

Quantity Price
1 £88.00 / 25µg
Estimated Shipment date
from Supplier 02-11-2016
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Description and Specification


Antigen Pokemon (LRF)
Applications Immunohistochemistry (Formalin/Paraffin)
Applications Western Blotting
Clone 1.30E+10
Concentration 0.5mg/mL
Conjugate Unlabeled
Format Purified
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Gene Alias Zbtb7a
Host Species Armenian Hamster
Isotype IgG
Quantity 25μg
Regulatory Status RUO
Species Reactivity Human
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal

This monoclonal antibody reacts with human Leukemia/lymphoma-related factor (LRF). This 65kDa protein is also known as POKEMON, FBI-1, and Zbtb7a. LRF is a member of the POK family of transcriptional repressors, and is expressed in hematopoietic stem cells, T and B lymphocytes, macrophages, and erythroid cells. This protein is also highly expressed in human non-Hodgkin’s lymphoma tissues and diffuse large B-cell lymphomas, demonstrating its prominent role in oncogenic transformation. Studies have demonstrated that LRF is also involved in B cell lineage commitment and development by opposing Notch signaling. Moreover, LRF is critical for erythroid terminal differentiation in the bone marrow by inhibiting Bim-mediated apoptosis. Finally, LRF interacts with Bcl-6 in germinal center B cells.