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Pokemon (LRF) Armenian Hamster anti-Human, Clone: 13E9, eBioscience™

Armenian Hamster Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-3309-80

UNSPSC : 12352200

Code : Z2

Additional Details : Weight : 0.01000kg

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Product Code. 15237347

  • £60.53 / 25µg


Estimated Shipment
01-08-2017
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Disclaimers:

For Research Use Only.


Specifications

Description

This monoclonal antibody reacts with human Leukemia/lymphoma-related factor (LRF). This 65kDa protein is also known as POKEMON, FBI-1, and Zbtb7a. LRF is a member of the POK family of transcriptional repressors, and is expressed in hematopoietic stem cells, T and B lymphocytes, macrophages, and erythroid cells. This protein is also highly expressed in human non-Hodgkin’s lymphoma tissues and diffuse large B-cell lymphomas, demonstrating its prominent role in oncogenic transformation. Studies have demonstrated that LRF is also involved in B cell lineage commitment and development by opposing Notch signaling. Moreover, LRF is critical for erythroid terminal differentiation in the bone marrow by inhibiting Bim-mediated apoptosis. Finally, LRF interacts with Bcl-6 in germinal center B cells.
Description & Specifications

Specifications

Pokemon (LRF)
1.30E+10
Unlabeled
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Armenian Hamster
25μg
Store at 2-8°C.
Monoclonal
Western Blot
0.5mg/mL
Purified
Zbtb7a
IgG
RUO
Primary
Human