Podocalyxin Mouse anti-Human, PE, Clone: B34D1.3, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 12-8873-41

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15597136

Quantity Price
1 £ 72.77 / 25 tests
Estimated Shipment date
from Supplier 04-05-2017
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Description and Specification

Specification

Concentration 5μL (0.5μg)/test
Host Species Mouse
Species Reactivity Human
Monoclonal or Polyclonal Monoclonal
Format Conjugated
Quantity 25 tests
Isotype IgG2a
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Antigen Podocalyxin
Gene Alias Gp200
Applications Flow Cytometry
Conjugate PE
Regulatory Status RUO
Primary or Secondary Primary
Clone B34D1.3

The monoclonal antibody B34D1.3 recognizes human podocalyxin, a protein expressed on undifferentiated human embryonic stem cells (ES), embryonic carcinoma cells (EC), and embryonic germ cells (EG). Podocalxyin is a heavily glycosylated cell adhesion protein with homology to CD34 and endoglycan. It was first identified on kidney podocytes, and then found to be upregulated in a variety of human cancers such as breast and prostate cancer. Like other stem cell-specific markers, the epitope recognized by the B34D1.3 antibody is lost upon cell differentiation.

The B34D1.3 antibody recognizes the ectodomain of podocalyxin, which is a different epitope from the Tra-1-60 and Tra-1-81 monoclonal antibodies. While Tra1-60 has been found to react with a sialidase-sensitive epitope, the epitope recognized by Tra1-81 has not been fully defined.