missing translation for 'onlineSavingsMsg'
Learn More

PNU 96415E, Tocris Bioscience™

D4 and 5-HT2A antagonist; antipsychotic

Brand:  Tocris (Bio-Techne) 273510

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 10mg

 View more versions of this product

Product Code. 13441834

  • £141.75 / 10mg

Estimated Shipment
28-06-2019

Please to purchase this item. Need a web account? Register with us today!


Description

Description

Antipsychotic agent. Displays high affinity for dopamine D4 and serotonergic 5-HT2A receptors and relatively weak affinity at D2 receptors (Ki values are 3.0, 5.8, 134, 181, 199, 240, 411 and > 678 nM for D4, 5-HT2A, 5-HT1A, α1, D2, D3, D1, α2 and muscarinic receptors respectively). Inhibits exploratory locomotor activity and antagonizes d-amphetamine-induced locomotor stimulation in rats.
Specifications

Chemical Identifiers

170856-41-4
413.358
1-2-3,4-dihydro-1h-2-benzopyran-1-yl ethyl-4-4-fluorophenyl piperazine dihydrochloride, 1-4-fluorophenyl-4-2-isochroman-1-yl ethyl piperazine dihydrochloride, 1-2-3,4-dihydro-1h-2-benzopyran-1-yl ethyl-4-4-fluorophenyl piperazinedihydrochloride
1-[2-(3,4-dihydro-1H-isochromen-1-yl)ethyl]-4-(4-fluorophenyl)piperazine;dihydrochloride
C21H27Cl2FN2O
OGMGYKPECFQXJJ-UHFFFAOYSA-N
9909647
C1COC(C2=CC=CC=C21)CCN3CCN(CC3)C4=CC=C(C=C4)F.Cl.Cl

Specifications

PNU 96415E
170856-41-4
1-2-3,4-dihydro-1h-2-benzopyran-1-yl ethyl-4-4-fluorophenyl piperazine dihydrochloride, 1-4-fluorophenyl-4-2-isochroman-1-yl ethyl piperazine dihydrochloride, 1-2-3,4-dihydro-1h-2-benzopyran-1-yl ethyl-4-4-fluorophenyl piperazinedihydrochloride
C1COC(C2=CC=CC=C21)CCN3CCN(CC3)C4=CC=C(C=C4)F.Cl.Cl
413.358
413.36
10mg
C21H27Cl2FN2O
OGMGYKPECFQXJJ-UHFFFAOYSA-N
1-[2-(3,4-dihydro-1H-isochromen-1-yl)ethyl]-4-(4-fluorophenyl)piperazine;dihydrochloride
9909647
>98%
Videos