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PNU 120596, Tocris Bioscience™

Positive allosteric modulator of α7 nAChR; active in vivo

Brand:  Tocris (Bio-Techne) 249850

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 50mg

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Product Code. 13461344

  • £587.49 / 50mg


Estimated Shipment
29-11-2018
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Description

Description

Positive allosteric modulator of α7 neuronal nicotinic acetylcholine receptors (EC50 = 216 nM), with no detectable effect on α4β2, α3β4 and α9α10 receptors. Active in vivo following systemic administration. Neuroprotective in an in vivo model of transient focal cerebral ischemia.
Specifications

Chemical Identifiers

501925-31-1
311.722
1-5-chloro-2,4-dimethoxyphenyl-3-5-methylisoxazol-3-yl urea, 1-5-chloro-2,4-dimethoxyphenyl-3-5-methyl-1,2-oxazol-3-yl urea, n-5-chloro-2,4-dimethoxyphenyl-n'-5-methyl-3-isoxazolyl-urea, d03fpq, pnu hplc, n-5-chloro-2,4-dimethoxphenyl-n'-5-methyl-3-isoxazolyl urea, 1-5-chloro-2,4-dimethoxy-phenyl-3-5-methyl-isoxazol-3-yl-urea, urea, n-5-chloro-2,4-dimethoxyphenyl-n'-5-methyl-3-isoxazolyl
1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methyl-1,2-oxazol-3-yl)urea
C13H14ClN3O4
CEIIEALEIHQDBX-UHFFFAOYSA-N
311434
CC1=CC(=NO1)NC(=O)NC2=CC(=C(C=C2OC)OC)Cl

Specifications

PNU 120596
501925-31-1
1-5-chloro-2,4-dimethoxyphenyl-3-5-methylisoxazol-3-yl urea, 1-5-chloro-2,4-dimethoxyphenyl-3-5-methyl-1,2-oxazol-3-yl urea, n-5-chloro-2,4-dimethoxyphenyl-n'-5-methyl-3-isoxazolyl-urea, d03fpq, pnu hplc, n-5-chloro-2,4-dimethoxphenyl-n'-5-methyl-3-isoxazolyl urea, 1-5-chloro-2,4-dimethoxy-phenyl-3-5-methyl-isoxazol-3-yl-urea, urea, n-5-chloro-2,4-dimethoxyphenyl-n'-5-methyl-3-isoxazolyl
CC1=CC(=NO1)NC(=O)NC2=CC(=C(C=C2OC)OC)Cl
311.722
311.72
50mg
C13H14ClN3O4
CEIIEALEIHQDBX-UHFFFAOYSA-N
1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methyl-1,2-oxazol-3-yl)urea
311434
>99%
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