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PNU 120596, Tocris Bioscience™

Positive allosteric modulator of α7 nAChR; active in vivo

Brand:  Tocris (Bio-Techne) 2498/10

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 10mg

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Product Code. 13451344

  • £174.93 / 10mg

Estimated Shipment date
from Supplier 31-03-2020

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Description

Description

Positive allosteric modulator of α7 neuronal nicotinic acetylcholine receptors (EC50 = 216 nM), with no detectable effect on α4β2, α3β4 and α9α10 receptors. Active in vivo following systemic administration. Neuroprotective in an in vivo model of transient focal cerebral ischemia.
Specifications

Chemical Identifiers

501925-31-1
311.722
1-5-chloro-2,4-dimethoxyphenyl-3-5-methylisoxazol-3-yl urea, 1-5-chloro-2,4-dimethoxyphenyl-3-5-methyl-1,2-oxazol-3-yl urea, n-5-chloro-2,4-dimethoxyphenyl-n'-5-methyl-3-isoxazolyl-urea, d03fpq, pnu hplc, n-5-chloro-2,4-dimethoxphenyl-n'-5-methyl-3-isoxazolyl urea, 1-5-chloro-2,4-dimethoxy-phenyl-3-5-methyl-isoxazol-3-yl-urea, urea, n-5-chloro-2,4-dimethoxyphenyl-n'-5-methyl-3-isoxazolyl
1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methyl-1,2-oxazol-3-yl)urea
C13H14ClN3O4
CEIIEALEIHQDBX-UHFFFAOYSA-N
311434
CC1=CC(=NO1)NC(=O)NC2=CC(=C(C=C2OC)OC)Cl

Specifications

10mg
501925-31-1
1-5-chloro-2,4-dimethoxyphenyl-3-5-methylisoxazol-3-yl urea, 1-5-chloro-2,4-dimethoxyphenyl-3-5-methyl-1,2-oxazol-3-yl urea, n-5-chloro-2,4-dimethoxyphenyl-n'-5-methyl-3-isoxazolyl-urea, d03fpq, pnu hplc, n-5-chloro-2,4-dimethoxphenyl-n'-5-methyl-3-isoxazolyl urea, 1-5-chloro-2,4-dimethoxy-phenyl-3-5-methyl-isoxazol-3-yl-urea, urea, n-5-chloro-2,4-dimethoxyphenyl-n'-5-methyl-3-isoxazolyl
CC1=CC(=NO1)NC(=O)NC2=CC(=C(C=C2OC)OC)Cl
311.722
311.72
PNU 120596
C13H14ClN3O4
CEIIEALEIHQDBX-UHFFFAOYSA-N
1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methyl-1,2-oxazol-3-yl)urea
311434
>99%
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