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PLZF, Alexa Fluor 488, clone: Mags.21F7, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 53-9320-80

Code : NEW

Additional Details : Weight : 0.09500kg

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Product Code. 15570267

  • £80.57 / 25µg


EU Stock 3
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Description

Description

Description: This Mags.21F7 monoclonal antibody reacts with human and mouse promyelocytic leukemia zinc finger (PLZF), a member of the BTB-POZ family of transcription factors. Expression of this transcriptional repressor in immune cells differs between mice and humans. In mice, PLZF is highly expressed in immature CD1d-resricted NKT2 and NKT1 cells, and a subset of gamma delta (Vg1.1+Vd6.3+) T cells. Studies have also demonstrated expression of PLZF in non-invariant CD1d-restricted T cells, as well as non-CD1d-restricted innate T cells. In humans, PLZF is expressed in NK cells, gamma delta T cells, as well as CD4 and CD8+ T cells. PLZF is also expressed in MR1-specific mucosal-associated invariant T cells, as well as in MHC Class II-restricted T cells that develop via a thymocyte-thymocyte interaction in humans. PLZF exists as a homodimer or in complex with PLZP, and has been shown to be involved in the development of NKT cells, NK cell function, cellular quiescence, and growth suppression. Finally, PLZF has been shown to inhibit gene expression induced by retinoic acid receptor.Applications Reported: This Mags.21F7 antibody has been reported for use in intracellular staining followed by flow cytometric analysis.Applications Tested: This Mags.21F7 antibody has been tested by intracellular staining followed by flow cytometric analysis of mouse thymocytes. This can be used at less than or equal to 1 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Excitation: 488 nm; Emission: 519 nm; Laser: Blue Laser.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

PLZF
Monoclonal
0.5mg/mL
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
Q05516
Zinc finger and BTB domain-containing protein 16, Zinc finger protein PLZF, Promyelocytic leukemia zinc finger protein, Zinc finger protein 145, ZNF145, PLZF, ZBTB16
Murine
Affinity chromatography
RUO
Antibody
Monoclonal
Murine
Flow Cytometry
Mags.21F7
Alexa Fluor 488
ZBTB16
Conjugated
ZBTB16
IgG1, kappa
25μg
Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary
7704
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