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PJ 34 hydrochloride, Tocris Bioscience™

Potent PARP inhibitor

Brand:  Tocris (Bio-Techne) 325510

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 10mg

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Product Code. 13432664

  • £144.06 / 10mg

Estimated Shipment date
from Supplier 30-03-2020

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Description

Description

Potent inhibitor of poly(ADP-ribose) polymerase (PARP) (EC50 = 20 nM). ∽1000-fold more potent than 3-Aminobenzamide (Cat. No. 0788). Protects primary neuronal cells from oxygen-glucose deprivation in vitro and reduces infarct size following focal cerebral ischemia in vivo. Displays protective effects against cisplatin -induced kidney injury. Also displays activity at Pim-1 and Pim-2 kinases at higher concentrations (IC50 values are 3.7 and 16 μM respectively).
Specifications

Chemical Identifiers

344458-15-7
331.8
pj34 hydrochloride, parp inhibitor viii, pj34, pj 34 hydrochloride, 2-dimethylamino-n-6-oxo-5,6-dihydrophenanthridin-2-yl acetamide hydrochloride, pj34 hcl, n-6-oxo-5,6-dihydrophenanthridin-2-yl-2-n,n-dimethylamino acetamide hydrochloride, 2-dimethylamino-n-6-oxo-5h-phenanthridin-2-yl acetamide hydrochloride, n-6-oxo-5,6-dihydrophenanthridin-2-yl-n,n-dimethylamino acetamide hydrochloride, pj 34 hcl
2-(dimethylamino)-N-(6-oxo-5H-phenanthridin-2-yl)acetamide;hydrochloride
C17H18ClN3O2
RURAZZMDMNRXMI-UHFFFAOYSA-N
16760621
CN(C)CC(=O)NC1=CC2=C(C=C1)NC(=O)C3=CC=CC=C32.Cl

Specifications

10mg
344458-15-7
pj34 hydrochloride, parp inhibitor viii, pj34, pj 34 hydrochloride, 2-dimethylamino-n-6-oxo-5,6-dihydrophenanthridin-2-yl acetamide hydrochloride, pj34 hcl, n-6-oxo-5,6-dihydrophenanthridin-2-yl-2-n,n-dimethylamino acetamide hydrochloride, 2-dimethylamino-n-6-oxo-5h-phenanthridin-2-yl acetamide hydrochloride, n-6-oxo-5,6-dihydrophenanthridin-2-yl-n,n-dimethylamino acetamide hydrochloride, pj 34 hcl
CN(C)CC(=O)NC1=CC2=C(C=C1)NC(=O)C3=CC=CC=C32.Cl
331.8
331.8
PJ 34 hydrochloride
C17H18ClN3O2
RURAZZMDMNRXMI-UHFFFAOYSA-N
2-(dimethylamino)-N-(6-oxo-5H-phenanthridin-2-yl)acetamide;hydrochloride
16760621
>98%
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