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PIT 1, Tocris Bioscience™

PIP3 antagonist. Blocks PIP3-PH interaction; inhibits Akt signaling

Brand:  Tocris (Bio-Techne) 416810

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 10mg

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Product Code. 13454274

  • £155.82 / 10mg

Estimated Shipment date
from Supplier 30-03-2020

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Description

Description

Selective PIP3 antagonist. Blocks the binding of PIP3 to the pleckstrin homology (PH) domain of Akt (IC50 = 31.03 μM). Inhibits cancer cell survival and induces apoptosis by inhibition of PIP3-dependent PI 3-kinase/Akt signaling. Exhibits antitumor activity in vivo.
Specifications

Chemical Identifiers

53501-41-0
351.761
pit 1, pit-1, n-3-chloro-2-hydroxy-5-nitrophenyl carbamothioyl benzamide, n-3-chloro-2-hydroxy-5-nitrophenyl amino thioxomethyl benzamide, cbmicro_008144, 1-benzoyl-3-3-chloro-2-hydroxy-5-nitrophenyl thiourea, 3-benzoyl-1-3-chloro-2-hydroxy-5-nitrophenyl thiourea, pit 1/, n-3-chloro-2-hydroxy-5-nitro-phenyl carbamothioyl benzamide
N-[(3-chloro-2-hydroxy-5-nitrophenyl)carbamothioyl]benzamide
C14H10ClN3O4S
RIGXBXPAOGDDIG-UHFFFAOYSA-N
3664359
C1=CC=C(C=C1)C(=O)NC(=S)NC2=CC(=CC(=C2O)Cl)[N+](=O)[O-]

Specifications

10mg
53501-41-0
pit 1, pit-1, n-3-chloro-2-hydroxy-5-nitrophenyl carbamothioyl benzamide, n-3-chloro-2-hydroxy-5-nitrophenyl amino thioxomethyl benzamide, cbmicro_008144, 1-benzoyl-3-3-chloro-2-hydroxy-5-nitrophenyl thiourea, 3-benzoyl-1-3-chloro-2-hydroxy-5-nitrophenyl thiourea, pit 1/, n-3-chloro-2-hydroxy-5-nitro-phenyl carbamothioyl benzamide
C1=CC=C(C=C1)C(=O)NC(=S)NC2=CC(=CC(=C2O)Cl)[N+](=O)[O-]
351.761
351.76
PIT 1
C14H10ClN3O4S
RIGXBXPAOGDDIG-UHFFFAOYSA-N
N-[(3-chloro-2-hydroxy-5-nitrophenyl)carbamothioyl]benzamide
3664359
>99%
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