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Pifithrin-α hydrobromide, Tocris Bioscience™

p53 inhibitor. Also aryl hydrocarbon receptor agonist

Brand:  Tocris (Bio-Techne) 126750

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 50mg

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Product Code. 13439023

  • £618.87 / 50mg

Estimated Shipment date
from Supplier 17-12-2019

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Description

Description

Inhibitor of p53; reversibly blocks p53-dependent transcriptional activation and apoptosis. Protects against neuronal death in models of stroke and neurodegenerative disorders. Active in vivo; protects mice from the side-effects of cancer therapy associated with p53 induction. Supresses self-renewal of embryonic stem cells. Also aryl hydrocarbon receptor (AHR) agonist, causes upregulation of AHR target gene CYP1A1 (EC50 = 1.1 μM). Cyclic analog available (Cat. No. 3843).
Specifications

Chemical Identifiers

63208-82-2
367.305
pifithrin-alpha, 2-2-imino-4,5,6,7-tetrahydrobenzothiazol-3-yl-1-p-tolylethanone, hbr, pifithrin-alpha mi, pft-alpha, pifithrin, pifithrin-alpha hydrobromide, unii-d213b92s1y, pifithrin-, a pft, a, 2-2-imino-4,5,6,7-tetrahydrobenzothiazol-3-yl-1-p-tolylethanone hydrobromide, 2-2-imino-4,5,6,7-tetrahydrobenzo d thiazol-3 2h-yl-1-p-tolylethanone hydrobromide
2-(2-imino-4,5,6,7-tetrahydro-1,3-benzothiazol-3-yl)-1-(4-methylphenyl)ethanone;hydrobromide
C16H19BrN2OS
HAGVCKULCLQGRF-UHFFFAOYSA-N
9929138
CC1=CC=C(C=C1)C(=O)CN2C3=C(CCCC3)SC2=N.Br

Specifications

50mg
63208-82-2
pifithrin-alpha, 2-2-imino-4,5,6,7-tetrahydrobenzothiazol-3-yl-1-p-tolylethanone, hbr, pifithrin-alpha mi, pft-alpha, pifithrin, pifithrin-alpha hydrobromide, unii-d213b92s1y, pifithrin-, a pft, a, 2-2-imino-4,5,6,7-tetrahydrobenzothiazol-3-yl-1-p-tolylethanone hydrobromide, 2-2-imino-4,5,6,7-tetrahydrobenzo d thiazol-3 2h-yl-1-p-tolylethanone hydrobromide
CC1=CC=C(C=C1)C(=O)CN2C3=C(CCCC3)SC2=N.Br
367.305
367.3
Pifithrin-α hydrobromide
C16H19BrN2OS
HAGVCKULCLQGRF-UHFFFAOYSA-N
2-(2-imino-4,5,6,7-tetrahydro-1,3-benzothiazol-3-yl)-1-(4-methylphenyl)ethanone;hydrobromide
9929138
>98%
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