Thermo Scientific™ Pierce™ TCEP·HCl

Reduce protein and peptide disulfide bonds using this thiol-free, pure, crystalline tris (2-carboxyethyl) phosphine hydrochloride, TCEP (CAS 5961-85-3).

Brand: Thermo Scientific™

Manufacturer Part Number: 20491

UNSPSC: 12161502

Code: PN

Additional Details:
Additional Details: CAS Number: 51805-45-9 Weight: 1.81440kg Transport: UN number : 3261 Chem class : 1a Pack group : II

Product Code. 11856784

Quantity Price
1 £ 341.0 / 10g
EU Stock 32
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Description and Specification


Formulation Crystalline powder of Tris(2-carboxyethyl)phosphine hydrochloride
Sufficient For Preparing nearly 700mL of 50mM solution
Description Pierce TCEP-HCl
Quantity 10g


  • Reduces even the most stable water-soluble alkyl disulfides
  • Effective at room temperature and pH 5 in less than five minutes
  • Does not require removal before reaction with maleimide or haloacetyl compounds
  • Water solubility of 310g/L
  • Resistant to air oxidation; nonvolatile and nonreactive toward other functional groups in proteins


Technical documents