Thermo Scientific™ Pierce™ DSP Crosslinker

Crosslink amines to amines with dithiobis succinimidyl propionate, composed of NHS-ester groups and disulfide-containing, 12.0A spacer arm and cleavable with reducing agents.

Brand: Thermo Scientific™

Manufacturer Part Number: 22586

UNSPSC: 12161502

Code: PN

Additional Details:
Additional Details: Weight: 0.45360kg

Product Code. 11821315

Quantity Price
1 £ 111.0 / 50mg
EU Stock 16
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Description and Specification


Spacer Arm Length 12Å
Formulation Dithiobis(succinimidylpropionate); powder solid
Cleavable Yes
Molecular Weight 404.42
Sufficient For 124mL of typical 1X (1mM) reaction solution, or approx. 25 uses at 2mg reagent per use
Description Pierce DSP (Lomant's Reagent)
Membrane Permeable Yes
PEGylated No
Chemical Reactivity Amine-to-Amine
Quantity 50mg
Water Soluble No


  • Cleavable by reducing agents
  • Membrane-permeable
  • Acylate in aqueous or organic media within two minutes at room temperature
  • Four- to five-hour half-life of ester at pH 7.0
  • Reactive groups: NHS ester (homobifunctional)
  • Reactive toward: amino groups


Technical documents