Thermo Scientific™ Pierce™ DSP Crosslinker

Crosslink amines to amines with dithiobis succinimidyl propionate, composed of NHS-ester groups and disulfide-containing, 12.0A spacer arm and cleavable with reducing agents.

Brand: Thermo Scientific™

Manufacturer Part Number: 22585

DSP (Lomant's Reagent, (Dithiobis¢succinimidylpropionate!) Store in fridge at 4C

UNSPSC: 12161502

Code: PN

Additional Details:
Additional Details: Weight: 1.81440kg

Product Code. 10731945

Quantity Price
1 £ 202.0 / 1g
EU Stock 16
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Description and Specification


Chemical Reactivity Amine-to-Amine
Cleavable Yes
Description Pierce DSP (Lomant's Reagent)
Formulation Dithiobis(succinimidylpropionate); powder solid
Membrane Permeable Yes
Molecular Weight 404.42
PEGylated No
Quantity 1g
Sufficient For 2473mL of typical 1X (1mM) reaction solution, or approx. 500 uses at 2mg reagent per use
Spacer Arm Length 12Ă…
Water Soluble No


  • Cleavable by reducing agents
  • Membrane-permeable
  • Acylate in aqueous or organic media within two minutes at room temperature
  • Four- to five-hour half-life of ester at pH 7.0
  • Reactive groups: NHS ester (homobifunctional)
  • Reactive toward: amino groups


Technical documents