Thermo Scientific™ Pierce™ DMP Crosslinker

Crosslink amines to amines with dimethyl pimelimidate (CAS 58537-94-3); composed of imidoester groups and a membrane-permeable, 7-atom spacer arm.

Brand: Thermo Scientific™

Manufacturer Part Number: 21667

UNSPSC: 12161502

Code: PN

Additional Details:
Additional Details: Weight: 1.81440kg

Product Code. 10740815

Quantity Price
1 £ 51.25 / 1g
EU Stock 11
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Description and Specification


Spacer Arm Length 9.2Å
Formulation Dimethyl pimelimidate-2HCl; powder solid
Cleavable No
Sufficient For 3858mL of typical 1X (1mM) reaction solution, or approx. 500 uses at 2mg reagent per use
Molecular Weight 259.17
Description Pierce DMP
Membrane Permeable Yes
PEGylated No
Chemical Reactivity Amine-to-Amine
Quantity 1g
Water Soluble Yes


  • Water-soluble
  • Rapid reaction with amines at alkaline pH values (pH 8-10)
  • Amidine bond retains net charge character of protein
  • Reversible at high pH values
  • Reactive groups: imidoester (homobifunctional)
  • Reactive toward: amino groups


Technical documents