missing translation for 'onlineSavingsMsg'
Learn More

Thermo Scientific™ iodoTMTsixplex™ Isobaric Mass Tagging Kit

Perform measurement of protein and peptide cysteine modifications (S-nitrosylation, oxidation and disulfide bridges) by multiplex quantitative mass spectrometry.

Brand:  Thermo Scientific™ 90103

Code : PN

Additional Details : Weight : 0.01000kg Transport : UN number : 3316 Chem class : 9 Pack group : III

Product Code. 13434289

  • £2270.00 / Pack of 5


In stock, ready to ship: 2
Add to basket

Description

Description

Tandem Mass Tag™ (TMT™) Reagents enable concurrent identification and multiplexed quantitation of proteins in different samples using tandem mass spectrometry. The iodoTMT™ Reagents are sets of isobaric (mass and structure) isomers that are iodoacetyl-activated for covalent, irreversible labeling of sulfhydryl (-SH) groups. Similar to iodoacetamide, iodoTMT Reagents react specifically with reduced cysteines (Cys) in peptides and proteins. IodoTMT Reagents can be differentiated by mass spectrometry (MS), enabling quantitation of the relative abundance of cysteine modifications, such as S–nitrosylation, oxidation and disulfide bonds, in cultured cells grown or treated with different conditions.

Highlights:

  • Specific – only reacts with sulfhydryl groups (reduced, unmodified cysteine residues)

  • Irreversible – labeled proteins and peptides are not susceptible to reducing agents

  • Flexible – options for duplex isotopic (MS) or sixplex isobaric (MS/MS) quantitation

  • Versatile – can be used to study cysteine modifications (e.g. di-sulfide bridges, S-nitrosylation)

Note:

IodoTMT Products replace our previously offered CysTMT Reagents, which utilized a dithiopyridine reactive group to reversibly label cysteine sulfhydryls.

Specifications

Specifications

• iodoTMT6-126 Label Reagent, 5 x 0.2 mg
• iodoTMT6-127 Label Reagent, 5 x 0.2 mg
• iodoTMT6-128 Label Reagent, 5 x 0.2 mg
• iodoTMT6-129 Label Reagent, 5 x 0.2 mg
• iodoTMT6-130 Label Reagent, 5 x 0.2 mg
• iodoTMT6-131 Label Reagent, 5 x 0.2 mg
• HES Buffer, 15 mL
• Bond-Breaker TCEP Solution, 0.5 mL
• DTT, No-Weigh Format, 8 x 7.7 mg
• Trypsin, 5 x 20 µg
• Trypsin Storage Solution, 250 µL
• Albumin (bovine), 2.5 mg

Upon receipt store all products at -20°C
iodoTMTsixplex™
Mass Spectrometry
Mass Spectrometer
iodoTMTsixplex Isobaric Mass Tag Labeling Kit
Tandem Mass Tag™ (TMT) Labels
Protein Labeling
Protein
Cell Lysate
Videos
Documents