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Phospho-SYK (Y348) Mouse anti-Human, Mouse, APC, Clone: moch1ct, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 17-9014-42

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15578216

  • £188.93 / 100 tests


EU Stock 1
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Disclaimers:

For Research Use Only.


Description

Description

This moch1ct monoclonal antibody recognizes human and mouse spleen tyrosine kinase (also known as SYK) when phosphorylated on tyrosine 348 (Y348). SYK is the founding member of the SYK family of kinases that also includes ZAP-70 (zeta-associated protein of 70 kD) and is expressed in hematopoietic cells, including B lymphocytes, immature (CD4, CD8 double-negative and double-positive) thymocytes, and myeloid cells, epithelial cell lines, and normal breast tissue. SYK is critical for B cell receptor (BCR) signaling and B cell development. Autophosphorylation of at Y348 is necessary for SYK to become fully catalytically active and creates a docking site for the SH2 domains of Vav, Grb2, p85 subunit of PI3 kinase, and PLC gamma.

Specificity of this moch1ct clone was confirmed by ELISA, flow cytometry, and western blotting.
Specifications

Specifications

Phospho-SYK (Y348)
moch1ct
Allophycocyanin
Conjugated
Murine
100 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry (Intracellular Staining)
5μL (0.06μg)/test
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Spleen tyrosine kinase, p72-Syk
IgG1
RUO
Primary
Murine
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