missing translation for 'onlineSavingsMsg'
Learn More

Phospho-Syk (Tyr348) Monoclonal Antibody (moch1ct), APC, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 17-9014-41

70.67 GBP valid until 2024-03-29
Use promo code "21615" to get your promotional price.



Code : NEW

Additional Details : Weight : 0.23750kg

 View more versions of this product

Product Code. 15568216

  • £106.00 / 25 tests
Estimated Shipment: 08-04-2024
to see stock.

Please to purchase this item. Need a web account? Register with us today!


Description

Description

Description: This moch1ct monoclonal antibody recognizes human and mouse spleen tyrosine kinase (also known as SYK) when phosphorylated on tyrosine 348 (Y348). SYK is the founding member of the SYK family of kinases that also includes ZAP-70 (zeta-associated protein of 70 kD) and is expressed in hematopoietic cells, including B lymphocytes, immature (CD4, CD8 double-negative and double-positive) thymocytes, and myeloid cells, epithelial cell lines, and normal breast tissue. SYK is critical for B cell receptor (BCR) signaling and B cell development. Autophosphorylation of at Y348 is necessary for SYK to become fully catalytically active and creates a docking site for the SH2 domains of Vav, Grb2, p85 subunit of PI3 kinase, and PLC gamma. Specificity of this moch1ct clone was confirmed by ELISA, flow cytometry, and western blotting. Applications Reported: This moch1ct antibody has been reported for use in intracellular staining followed by flow cytometric analysis. Applications Tested: This moch1ct antibody has been pre-titrated and tested by intracellular staining followed by flow cytometric analysis of stimulated mouse splenocytes. This can be used at 5 μL (0.06 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.

Phospho-Syk (Tyr348) Monoclonal antibody specifically detects Phospho-Syk (Tyr348) in Human, Mouse samples. It is validated for Flow Cytometry.
Specifications

Specifications

Phospho-Syk (Tyr348)
Monoclonal
5 μL/Test
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
P43405, P48025
Syk
Affinity chromatography
RUO
20963, 6850
4° C, store in dark, DO NOT FREEZE!
Liquid
Flow Cytometry
moch1ct
APC
Syk
DKFZp313N1010; EC 2.7.10.2; FLJ25043; FLJ37489; HGNC:11205; kinase Syk; KSYK; p72Syk; p72-Syk; ptk72; SP1; spleen associated tyrosine kinase; spleen tyrosine kinase; SYK; syk signaling; Sykb; tyrosine-kinase syk; tyrosine-protein kinase SYK
Mouse
25 Tests
Primary
Human, Mouse
Antibody
IgG1 κ
Product Suggestions

Product Suggestions

Videos
SDS
Documents

Documents

Certificates
Special Offers

Special Offers

For Research Use Only.