Phospho-STAT6 (Y641) Mouse anti-Human, Mouse, PerCP-eFluor 710, Clone: CHI2S4N, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 46-9013-42

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15599386

Quantity Price
1 £ 213.39 / 100 tests
Estimated Shipment date
from Supplier 09-05-2017
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Description and Specification

Specification

Concentration 5μL (0.03μg)/test
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Gene Alias signal transducer and activator of transcription 6, pSTAT6
Isotype IgG2a
Regulatory Status RUO
Quantity 100 tests
Monoclonal or Polyclonal Monoclonal
Conjugate PerCP-eFluor 710
Clone CHI2S4N
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
Format Conjugated
Antigen Phospho-STAT6 (Y641)
Applications Flow Cytometry (Intracellular Staining)
Species Reactivity Human, Mouse
Host Species Mouse
Primary or Secondary Primary

This CHI2S4N monoclonal antibody recognizes human and mouse signal transducer and activator of transcription 6 (STAT6) when phosphorylated on tyrosine 641. Following their phosphorylation by JAKs, STAT proteins translocate to the nucleus where they bind to DNA and regulate transcription of specific genes in a cell type- and cytokine-specific manner. In response to IL-4, STAT6 is phosphorylated on tyrosine 641 by JAK1 and JAK3. STAT6 signaling downstream of the IL-4 receptor promotes T cell growth and B cell production of IgE.

Specificity of this CHI2S4N clone was determined by ELISA and flow cytometry.