Phospho-STAT6 (Y641) Mouse anti-Human, Mouse, PerCP-eFluor 710, Clone: CHI2S4N, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 46-9013-42

100TEST Anti-Human/Mouse phospho-STAT6 (Y641) PerCP-eFluor 710

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15599386

Quantity Price
1 £ 325.2 / 100 tests
Estimated Shipment date
from Supplier 21-02-2017
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Description and Specification

Specification

Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Gene Alias signal transducer and activator of transcription 6, pSTAT6
Isotype IgG2a
Regulatory Status RUO
Concentration 5μL (0.03μg)/test
Antigen Phospho-STAT6 (Y641)
Format Conjugated
Host Species Mouse
Applications Flow Cytometry (Intracellular Staining)
Quantity 100 tests
Species Reactivity Human, Mouse
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Clone CHI2S4N
Conjugate PerCP-eFluor 710

This CHI2S4N monoclonal antibody recognizes human and mouse signal transducer and activator of transcription 6 (STAT6) when phosphorylated on tyrosine 641. Following their phosphorylation by JAKs, STAT proteins translocate to the nucleus where they bind to DNA and regulate transcription of specific genes in a cell type- and cytokine-specific manner. In response to IL-4, STAT6 is phosphorylated on tyrosine 641 by JAK1 and JAK3. STAT6 signaling downstream of the IL-4 receptor promotes T cell growth and B cell production of IgE.

Specificity of this CHI2S4N clone was determined by ELISA and flow cytometry.