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Phospho-STAT6 (Y641) Mouse anti-Human, Mouse, PE, Clone: CHI2S4N, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 12-9013-42

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15527156

  • £188.93 / 100 tests


EU Stock 3
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Disclaimers:

For Research Use Only.


Description

Description

This CHI2S4N monoclonal antibody recognizes human and mouse signal transducer and activator of transcription 6 (STAT6) when phosphorylated on tyrosine 641. Following their phosphorylation by JAKs, STAT proteins translocate to the nucleus where they bind to DNA and regulate transcription of specific genes in a cell type- and cytokine-specific manner. In response to IL-4, STAT6 is phosphorylated on tyrosine 641 by JAK1 and JAK3. STAT6 signaling downstream of the IL-4 receptor promotes T cell growth and B cell production of IgE.

Specificity of this CHI2S4N clone was determined by ELISA and flow cytometry.
Specifications

Specifications

Phospho-STAT6 (Y641)
CHI2S4N
PE
Conjugated
Murine
100 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry (Intracellular Staining)
5μL (0.125μg)/test
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
signal transducer and activator of transcription 6, pSTAT6
IgG2a
RUO
Primary
Murine