Phospho-STAT6 (Y641) Mouse anti-Human, Mouse, PE, Clone: CHI2S4N, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 12-9013-41

UNSPSC: 12352203

Code: Z2

Additional Details:
Additional Details: Weight: 0.00250kg



Disclaimers: For Research Use Only.

Product Code. 15202635

Quantity Price
1 £ 78.88 / 25 tests
EU Stock 3
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Description and Specification

Specification

Antigen Phospho-STAT6 (Y641)
Applications Flow Cytometry (Intracellular Staining)
Clone CHI2S4N
Concentration 5μL (0.125μg)/test
Conjugate PE
Format Conjugated
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Gene Alias signal transducer and activator of transcription 6, pSTAT6
Host Species Murine
Isotype IgG2a
Quantity 25 Tests
Regulatory Status RUO
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Target Species Human
Target Species Murine

This CHI2S4N monoclonal antibody recognizes human and mouse signal transducer and activator of transcription 6 (STAT6) when phosphorylated on tyrosine 641. Following their phosphorylation by JAKs, STAT proteins translocate to the nucleus where they bind to DNA and regulate transcription of specific genes in a cell type- and cytokine-specific manner. In response to IL-4, STAT6 is phosphorylated on tyrosine 641 by JAK1 and JAK3. STAT6 signaling downstream of the IL-4 receptor promotes T cell growth and B cell production of IgE.

Specificity of this CHI2S4N clone was determined by ELISA and flow cytometry.