Phospho-STAT6 (Y641) Mouse anti-Human, Mouse, PE, Clone: CHI2S4N, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 12-9013-41

Anti-Human/Mouse phospho-STAT6 (Y641) PE

UNSPSC: 12352203

Code: Z2

Additional Details:
Additional Details: Weight: 0.00250kg



Disclaimers: For Research Use Only.

Product Code. 15202635

Quantity Price
1 £ 78.88 / 25 tests
Estimated Shipment date
from Supplier 28-03-2017
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Description and Specification

Specification

Antigen Phospho-STAT6 (Y641)
Format Conjugated
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Applications Flow Cytometry (Intracellular Staining)
Isotype IgG2a
Quantity 25 tests
Regulatory Status RUO
Species Reactivity Human, Mouse
Gene Alias signal transducer and activator of transcription 6, pSTAT6
Host Species Mouse
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Clone CHI2S4N
Concentration 5μL (0.125μg)/test
Conjugate PE

This CHI2S4N monoclonal antibody recognizes human and mouse signal transducer and activator of transcription 6 (STAT6) when phosphorylated on tyrosine 641. Following their phosphorylation by JAKs, STAT proteins translocate to the nucleus where they bind to DNA and regulate transcription of specific genes in a cell type- and cytokine-specific manner. In response to IL-4, STAT6 is phosphorylated on tyrosine 641 by JAK1 and JAK3. STAT6 signaling downstream of the IL-4 receptor promotes T cell growth and B cell production of IgE.

Specificity of this CHI2S4N clone was determined by ELISA and flow cytometry.