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Phospho-p38 MAPK (T180/Y182) Mouse anti-Human, PerCP-eFluor 710, Clone: 4NIT4KK, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 46-9078-41

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15569396

  • £78.88 / 25 tests


EU Stock 2
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Disclaimers:

For Research Use Only.


Description

Description

This 4NIT4KK monoclonal antibody recognizes human and mouse p38 mitogen-activated protein kinase (MAPK) when phosphorylated on T180/Y182. p38 MAPK belongs to a family of conserved serine/threonine protein kinases that are phosphorylated and activated in response to numerous stress stimuli including TLR ligands (such as LPS), osmotic shock, heat shock, UV irradiation, and inflammatory cytokines. There are four p38 MAPK members that include p38 alpha, p38 beta, p38 gamma, and p38 delta. The primary activators of p38 MAPK are MKK3/4 and MKK6. Several downstream targets of p38 MAPK have been identified including MK2/3, p53, ATF-2, and ETS1. p38 MAPK can be negatively regulated by the chemical inhibitor SB203580. Specificity of this 4NIT4KK clone was determined by ELISA, flow cytometry, and western blotting.
Specifications

Specifications

Phospho-p38 MAPK (T180/Y182)
4NIT4KK
PerCP-eFluor 710
Conjugated
Murine
25 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
Monoclonal
Flow Cytometry (Intracellular Staining)
5μL (0.03μg)/test
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
p38 mitogen-activated protein kinase, RK, CSBP
IgG2b
RUO
Primary
Human
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