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PHA 568487, Tocris Bioscience™

α7-selective agonist

Brand:  Tocris (Bio-Techne) 313410

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 10mg

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Product Code. 13442494

  • £117.45 / 10mg

Estimated Shipment
09-07-2019

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Description

Description

Agonist of the α7 nicotinic acetylcholine receptor (Ki values are 44 and 2800 for α7 and 5-HT3 respectively, IC50 values are > 100 μM for α3β4 and α1β1δγ respectively, and % inhibition is < 1 and 5% for α4β2 and hERG respectively). Orally active and brain penetrant.
Specifications

Chemical Identifiers

527680-57-5
404.419
pha-568487 fumarate, n-3r-1-azabicyclo 2.2.2 oct-3-yl-2,3-dihydro-1,4-benzodioxin-6-carboxamide fumarate, unii-xfl65583pd, 1,4-benzodioxin-6-carboxamide, n-3r-1-azabicyclo 2.2.2 oct-3-yl-2,3-dihydro-, 2e-2-butenedioate 1:1
N-[(3R)-1-azabicyclo[2.2.2]octan-3-yl]-2,3-dihydro-1,4-benzodioxine-6-carboxamide;(E)-but-2-enedioic acid
C20H24N2O7
QYQZUGYJVHHHEE-QDSMGTAFSA-N
56972212
C1CN2CCC1C(C2)NC(=O)C3=CC4=C(C=C3)OCCO4.C(=CC(=O)O)C(=O)O

Specifications

PHA 568487
527680-57-5
pha-568487 fumarate, n-3r-1-azabicyclo 2.2.2 oct-3-yl-2,3-dihydro-1,4-benzodioxin-6-carboxamide fumarate, unii-xfl65583pd, 1,4-benzodioxin-6-carboxamide, n-3r-1-azabicyclo 2.2.2 oct-3-yl-2,3-dihydro-, 2e-2-butenedioate 1:1
C1CN2CCC1C(C2)NC(=O)C3=CC4=C(C=C3)OCCO4.C(=CC(=O)O)C(=O)O
404.419
404.41
10mg
C20H24N2O7
QYQZUGYJVHHHEE-QDSMGTAFSA-N
N-[(3R)-1-azabicyclo[2.2.2]octan-3-yl]-2,3-dihydro-1,4-benzodioxine-6-carboxamide;(E)-but-2-enedioic acid
56972212
>99%
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