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PFI 1, Tocris Bioscience™

BET bromodomain inhibitor

Brand:  RD Systems (Bio-Techne) 4445/50

Code : Z1

Additional Details : Weight : 0.00050kg

Quantity 50mg

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Product Code. 13464774

  • £625.89 / 50mg


Estimated Shipment
03-09-2018
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Description

Description

Potent BET bromodomain inhibitor; exhibits inhibitory activity at bromodomain-containing protein (BRD) 2 and BRD4 (IC50 values are 98 and 220 nM respectively). Induces apoptosis and G1 cell cycle arrest in BET inhibitor-sensitive cell lines (MV4;11). Also downregulates Aurora B expression in MV4;11 cells. Cell permeable.
Specifications

Chemical Identifiers

1403764-72-6
347.389
2-Methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide
C16H17N3O4S
TXZPMHLMPKIUGK-UHFFFAOYSA-N
71271629

Specifications

PFI 1
1403764-72-6
C16H17N3O4S
TXZPMHLMPKIUGK-UHFFFAOYSA-N
2-methoxy-N-(3-methyl-2-oxo-1,4-dihydroquinazolin-6-yl)benzenesulfonamide
71271629
50mg
>98%
2-Methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide
CN1CC2=C(C=CC(=C2)NS(=O)(=O)C3=CC=CC=C3OC)NC1=O
347.389
347.39
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