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PF 915275, Tocris Bioscience™

Potent and selective 11β-hydroxysteroid dehydrogenase inhibitor

Brand:  Tocris (Bio-Techne) 329150

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 50mg

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Product Code. 13462724

  • £568.00 / 50mg


Estimated Shipment
02-07-2018
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Description

Description

Potent and selective 11β-hydroxysteroid dehydrogenase type 1 (11βHSD1) inhibitor (Ki = 2.3 nM) that displays little activity at 11βHSD2 (1.5% inhibition at 10μM). Inhibits the conversion of prednisone to prednisolone in human hepatocytes in vitro (EC50 = 15 nM) and has antidiabetic activity in vivo. Orally active.
Specifications

Chemical Identifiers

PF 915275
C18H14N4O2S
350.39
N-(6-Amino-2-pyridinyl)-4'-cyano-[1, 1'-biphenyl]-4-sulfonamide

Specifications

PF 915275
>98%
C18H14N4O2S
N-(6-Amino-2-pyridinyl)-4'-cyano-[1, 1'-biphenyl]-4-sulfonamide
857290-04-1
50mg
350.39
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