PDE3B Rat anti-Mouse, Clone: SMCP3B, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-1973-82

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15217297

Quantity Price
1 £ 176.7 / 100µg
Estimated Shipment date
from Supplier 03-05-2017
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Description and Specification

Specification

Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Applications Western Blotting
Clone SMCP3B
Host Species Rat
Storage Requirements Store at 2-8°C.
Conjugate Unlabeled
Isotype IgG2a
Species Reactivity Mouse
Antigen PDE3B
Quantity 100μg
Format Purified
Concentration 0.5mg/mL
Primary or Secondary Primary
Gene Alias Phosphodiesterase 3b
Regulatory Status RUO
Monoclonal or Polyclonal Monoclonal

Cyclic nucleotide phosphodiesterases (PDE) catalyze the hydrolysis of cAMP and cGMP thereby regulating the effects of these second messengers. There are several families of PDE which share common structural organization. The PDE3 family has two members, 3A and 3B that are products of two separate genes. PDE3B (∽130 kDa) is expressed predominantly in adipose tissue and lymphocytes, while PDE3A (∽120 kDa) is expressed predominantly in platelets and heart tissue.

The monoclonal antibody SMCP3B reacts with mouse PDE3B. The SMCP3B antibody was generated against amino acids 643-1100 in the C-terminus and does not cross-react with mouse PDE3A, as determined by western blot analysis of lysates of mouse heart tissue. The SMCP3B antibody does not cross-react with human PDE3B.