PD 407824, Tocris Bioscience™

Selective inhibitor of Chk1 and Wee1

Brand:  Tocris (Bio-Techne) 269410

Product Code. 13461744

Description

Selective inhibitor of checkpoint kinases Chk1 and Wee1 (IC50 values are 47 and 97 nM respectively). Displays selectivity over a range of other protein kinases; IC50 values are 3.4, 3.75, > 5, > 50, > 50 and > 50 μM for PKC, CDK4, other CDKs, c-Src, PDGFR and FGFR respectively.

Chemical Identifiers

• CAS: 622864-54-4
• Molecular Weight (g/mol): 328.327
• Synonym: 9-Hydroxy-4-phenyl-pyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione

• Molecular Formula: C20H12N2O3
• InChI Key: IAUZTOZLTFSMIE-UHFFFAOYSA-N
• PubChem CID: 4369491

Specifications

• Chemical Name or Material: PD 407824
• CAS: 622864-54-4
• Molecular Formula: C20H12N2O3
• InChI Key: IAUZTOZLTFSMIE-UHFFFAOYSA-N
• IUPAC Name: 9-hydroxy-4-phenyl-6H-pyrrolo[3,4-c]carbazole-1,3-dione
• PubChem CID: 4369491

• Quantity: 10mg
• Purity Grade: >98%
• Synonym: 9-Hydroxy-4-phenyl-pyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione
• SMILES: C1=CC=C(C=C1)C2=CC3=C(C4=C(N3)C=CC(=C4)O)C5=C2C(=O)NC5=O
• Molecular Weight (g/mol): 328.327
• Formula Weight: 328.32