PD 407824, Tocris Bioscience™

Selective inhibitor of Chk1 and Wee1

Brand:  Tocris (Bio-Techne) 269410

Product Code. 13461744

Description

Selective inhibitor of checkpoint kinases Chk1 and Wee1 (IC50 values are 47 and 97 nM respectively). Displays selectivity over a range of other protein kinases; IC50 values are 3.4, 3.75, > 5, > 50, > 50 and > 50 μM for PKC, CDK4, other CDKs, c-Src, PDGFR and FGFR respectively.

Chemical Identifiers

• Chemical Name or Material: PD 407824
• Molecular Formula: C₂₀H₁₂N₂O₃
• Formula Weight: 328.32
• Synonym: 9-Hydroxy-4-phenyl-pyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione

Specifications

• Chemical Name or Material: PD 407824
• CAS: 622864-54-4
• Molecular Formula: C₂₀H₁₂N₂O₃
• Synonym: 9-Hydroxy-4-phenyl-pyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione

• Quantity: 10mg
• Purity Grade: >98%
• Formula Weight: 328.32