PD-1H Armenian Hamster anti-Mouse, Clone: MH5A, Functional Grade, eBioscience™

Armenian Hamster Monoclonal Antibody, Functional Grade

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 16-5919-82

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Disclaimers: For Research Use Only.

Product Code. 15597786

Quantity Price
1 £ 78.88 / 100µg
Estimated Shipment date
from Supplier 02-05-2017
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Description and Specification

Specification

Formulation aqueous buffer, no sodium azide
Applications Flow Cytometry
Format Purified
Species Reactivity Mouse
Antigen PD-1H
Conjugate Unlabeled
Host Species Armenian Hamster
Quantity 100μg
Primary or Secondary Primary
Isotype IgG
Monoclonal or Polyclonal Monoclonal
Regulatory Status RUO
Storage Requirements Store at 2-8°C.
Concentration 1mg/mL
Clone MH5A
Gene Alias VISTA

The monoclonal antibody MH5A reacts with a homolog of PD-1 (PD-1H) also known as VISTA. PD-1H is a 309 aa type I transmembrane protein that belongs to the CD28 superfamily. This cell surface receptor is expressed on nearly all hematopoietic cells except B cells. VISTA negatively regulates T cell responses by suppressing early TCR activation, inhibiting cell proliferation, and suppressing TH1 cytokine production.

The MH5A antibody has been reported to inhibit T cell infiltration in graft-versus-host disease mouse models.