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PD-1H, Functional Grade, clone: MH5A, eBioscience™

Armenian Hamster Monoclonal Antibody

Brand:  Affymetrix eBioscience 16-5919-82

Code : NEW

Additional Details : Weight : 0.09500kg

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Product Code. 15597786

  • £80.68 / 100µg


Estimated Shipment date
from Supplier 30-07-2018
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Description

Description

Description: The monoclonal antibody MH5A reacts with a homolog of PD-1 (PD-1H) also known as VISTA. PD-1H is a 309 aa type I transmembrane protein that belongs to the CD28 superfamily. This cell surface receptor is expressed on nearly all hematopoietic cells except B cells. VISTA negatively regulates T cell responses by suppressing early TCR activation, inhibiting cell proliferation, and suppressing TH1 cytokine production.The MH5A antibody has been reported to inhibit T cell infiltration in graft-versus-host disease mouse models.Applications Reported: This MH5A antibody has been reported for use in flow cytometric analysis.Applications Tested: This MH5A antibody has been tested by flow cytometric analysis of mouse splenocytes. This can be used at less than or equal to 0.25 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Storage and handling: Use in a sterile environment.Filtration: 0.2μm post-manufacturing filtered.Purity: Greater than 90%, as determined by SDS-PAGE.Endotoxin Level: Less than 0.001 ng/μg antibody, as determined by LAL assay.Aggregation: Less than 10%, as determined by HPLC.
Specifications

Specifications

PD-1H
Monoclonal
1mg/mL
PBS with no preservative; pH 7.2
Q9D659
VISTA
Armenian Hamster
Affinity chromatography
RUO
Antibody
Monoclonal
Murine
Flow Cytometry
MH5A
Functional Grade
Vsir
Purified
Vsir
IgG
100μg
Store at 2-8°C.
Primary
74048
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