missing translation for 'onlineSavingsMsg'
Learn More

PD 166793, Tocris Bioscience™

Broad spectrum MMP inhibitor

POA


Description

Description

Broad spectrum MMP inhibitor. Displays high affinity for MMP-2, -3 and -13 (IC50 values are 4, 7 and 8 nM respectively) and exhibits > 750-fold selectivity over MMP-1, -7 and -9. Attenuates left ventricular remodelling and dysfunction in rat model of heart failure.