Epredia™ Lab Vision™ Paxillin Ab-1 Mouse Monoclonal Antibody, 200μg/mL, BSA and azide

Provide accurate, reproducible results with the Epredia™ Paxillin Ab-1, Mouse Monoclonal Antibody.

Product Code	Brand	Form	Quantity
12611357	Epredia™ MS-404-P1	Concentrated	500 μL
12621357	Epredia™ MS-404-P1ABX	Concentrated	100 μL
12631357	Epredia™ MS-404-PABX	Concentrated	200 μL
12601357	Epredia™ MS-404-P0	Concentrated	100 μL
12681347	Epredia™ MS-404-P	Concentrated	1 mL
12671357	Epredia™ MS-404-R7	Prediluted	7 mL

Description

Paxillin is a focal adhesion protein and a substrate for several tyrosine kinases such as src, FAK, and p210BRC/ABL. The tyrosine phosphorylation of paxillin is affected by conditions that change cell-cell adhesion. Paxillin associates tightly with FAK and Crk through its SH2 domain. This interaction is independent of the extracellular matrix. Although paxillin was initially discovered in fibroblasts, its phosphorylation may also be important during neurite extension during differentiation.

Host Species: Mouse

Clone: 5H11

Isotype: IgG1/κ

Species Reactivity: Human and Rat. Others not known.

Epitope: Not determined

Immunogen: Purified recombinant full-length human paxillin protein

Molecular Weight: 68kDa

Positive Control: HeLa cells, Colon CA

Cellular Localization: Membrane and cytoplasmic

Recommended for:

• Immunohistochemistry (Formalin/paraffin)
• Western Blotting
• Immunofluorescence
• Immunoprecipitation (Native verified)

Note:

USA: RUO; Int'l: RUO

Specifications

• Antigen: Paxillin Ab-1
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Conjugate: Unconjugated
• Regulatory Status: RUO
• Target Species: Human, Rat
• Isotype: IgG2a κ

• Clone: 5H11
• Classification: Monoclonal
• Host Species: Mouse
• Research Discipline: Cytoskeletal Protein
• Immunogen: Purified recombinant full-length human paxillin protein
• Primary or Secondary: Primary