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PARP1 Mouse anti-Human, Clone: HC2R8, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-6667-82

Code : Z2

Additional Details : Weight : 0.01000kg

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Product Code. 15277927

  • £91.11 / 100µg


EU Stock 1
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Disclaimers:

For Research Use Only.


Description

Description

This HC2R8 monoclonal antibody reacts with human poly (ADP-ribose) polymerase (PARP1). This ubiquitous 116kDa nuclear enzyme is involved in DNA repair. During apoptosis, active caspases -3, -6 and -7 cleave PARP1 after Asp214, thereby inactivating PARP1 and generating two apoptotic fragments sized 85kDa and 25 kDa.

The HC2R8 antibody specifically recognizes both the cleaved and non-cleaved forms of PARP.
Specifications

Specifications

PARP1
HC2R8
Unlabeled
Purified
IgG2b
RUO
Primary
Human
Western Blot
0.5mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Murine
100μg
Store at 2-8°C.
Monoclonal