PARP1 Mouse anti-Human, Clone: HC2R8, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-6667-80

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15267927

Quantity Price
1 £ 54.42 / 25µg
Estimated Shipment date
from Supplier 03-05-2017
Add to basket


Description and Specification

Specification

Concentration 0.5mg/mL
Species Reactivity Human
Format Purified
Quantity 25μg
Antigen PARP1
Isotype IgG2b
Regulatory Status RUO
Host Species Mouse
Monoclonal or Polyclonal Monoclonal
Clone HC2R8
Primary or Secondary Primary
Conjugate Unlabeled
Storage Requirements Store at 2-8°C.
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Applications Western Blotting

This HC2R8 monoclonal antibody reacts with human poly (ADP-ribose) polymerase (PARP1). This ubiquitous 116kDa nuclear enzyme is involved in DNA repair. During apoptosis, active caspases -3, -6 and -7 cleave PARP1 after Asp214, thereby inactivating PARP1 and generating two apoptotic fragments sized 85kDa and 25 kDa.

The HC2R8 antibody specifically recognizes both the cleaved and non-cleaved forms of PARP.