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PARP1 (Cleaved) Mouse anti-Human, PE, Clone: HLNC4, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 12-6668-41

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15527076

  • £103.33 / 25 tests


Estimated Shipment date
from Supplier 30-06-2017
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Disclaimers:

For Research Use Only.


Specifications

Description

This HLNC4 monoclonal antibody reacts with human poly (ADP-ribose) polymerase (PARP1). This ubiquitous 116kDa nuclear enzyme is involved in DNA repair. During apoptosis, active caspases -3, -6 and -7 cleave PARP1 after Asp214, thereby inactivating PARP1 and generating two apoptotic fragments sized 85kDa and 25 kDa.

The HLNC4 antibody specifically recognizes the 85kDa PARP1 fragment produced after cleavage and does not recognize the full-length 116kDa protein.The following peptide was used as the immunogen: NH2-GVDEVAKKKSKKEKDC-COOH.
Description & Specifications

Specifications

PARP1 (Cleaved)
HLNC4
PE
aqueous buffer, 0.09% sodium azide, contains stabilizer if necessary
Murine
25 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry (Intracellular Staining)
5μL (0.004μg)/test
Conjugated
poly ADP-ribose polymerase
IgG2b
RUO
Primary
Human