PARP1 (Cleaved) Mouse anti-Human, PE, Clone: HLNC4, eBioscience™
Mouse Monoclonal Antibody
Brand: Affymetrix eBioscience 12-6668-41
Code : NEW
Additional Details : Weight : 0.23750kg
DescriptionThis HLNC4 monoclonal antibody reacts with human poly (ADP-ribose) polymerase (PARP1). This ubiquitous 116kDa nuclear enzyme is involved in DNA repair. During apoptosis, active caspases -3, -6 and -7 cleave PARP1 after Asp214, thereby inactivating PARP1 and generating two apoptotic fragments sized 85kDa and 25 kDa.
The HLNC4 antibody specifically recognizes the 85kDa PARP1 fragment produced after cleavage and does not recognize the full-length 116kDa protein.The following peptide was used as the immunogen: NH2-GVDEVAKKKSKKEKDC-COOH.
|Store at 2-8°C. Do not freeze. Light-sensitive material.|
|Flow Cytometry (Intracellular Staining)|
|aqueous buffer, 0.09% sodium azide, contains stabilizer if necessary|
|poly ADP-ribose polymerase|