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Pan Cytokeratin Monoclonal Antibody (AE1/AE3), eFluor™ 660, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 50-9003-82

Code : NEW

Additional Details : Weight : 0.09500kg

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Product Code. 15570057

  • £446.00 / 100µg
Estimated Shipment: 08-04-2024
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Description

Description

Description: The monoclonal antibodies AE1 and AE3 recognize many of the acidic and basic cytokeratin family members. Cytokeratins are intermediate filament proteins comprising one component of the cytoskeleton. There are two large families of cytokeratins, acidic and basic, but all contain the same basic domains (i.e. an alpha-helical core with an N- and C-terminal domain). The proteins are expressed in epithelial cells, but are developmentally regulated. Many tumors also express these proteins and their expression can help identify the origin of a neoplasm. The AE3 monoclonal antibody recognizes the 65 to 67 triplet, 64, 59, 58, 56, 54 and 52kD proteins also known as cytokeratin 1, 2, 3, 4, 5, 6, 7, and 8 while the AE1 antibody recognizes 56.5, 54', 50, 50', 48, and 40 kDa proteins (also known as CK10, 14, 15, 16 and 19). These antibodies can be used on a wide array of tissue samples from mouse, human, rat, primates (cynomolgus and rhesus), dog, cat, rabbit, and chicken. Applications Reported: This AE1/AE3 antibody has been reported for use in immunohistochemical staining, immunocytochemistry, immunohistochemical staining of frozen tissue sections, and immunohistochemical staining of formalin-fixed paraffin embedded tissue sections. Applications Tested: This AE1/AE3 antibody has been tested by immunocytochemistry on methanol-fixed MCF7 cells and can be used at less than or equal to 5 μg/mL.

Pan Cytokeratin Monoclonal antibody specifically detects Pan Cytokeratin in Canine, Human, Mouse, Non-human Primate, Rabbit, Rhesus Monkey samples. It is validated for Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot.
Specifications

Specifications

Pan Cytokeratin
Monoclonal
0.2 mg/mL
PBS with 0.09% sodium azide; pH 7.2
P02533, P02535, P02538, P04104, P04264, P05783, P05784, P05787, P07744, P08727, P08729, P08730, P08779, P11679, P12035, P13645, P13646, P13647, P19001, P19012, P19013, P35908, P50446, Q01546, Q04695, Q29426, Q3TTY5, Q3UV17, Q61414, Q61781, Q6EIY9, Q6EIZ0, Q6EIZ1, Q6IFZ6, Q7Z794, Q922U2, Q9DCV7, Q9QWL7, Q9Z2K1
KRT1, KRT10, KRT13, KRT14, KRT15, KRT16, KRT17, KRT18, KRT19, KRT2, KRT3, KRT4, KRT5, Krt6a, KRT7, KRT76, KRT77, KRT8
Affinity chromatography
RUO
100009029, 100341120, 100341376, 100344183, 100344942, 100345579, 100348388, 100348891, 100352658, 100353162, 100353415, 100353668, 100354174, 100424400, 100425096, 100426180, 100426330, 100682832, 100683333, 100683401, 100685323, 100685404, 100685481, 100687760, 103348273, 106994041, 110308, 110310, 16661, 16663, 16664, 16665, 16666, 16667, 16668, 16669, 16678, 16681, 16682, 16687, 16691, 374454, 3848, 3849, 3850, 3851, 3852, 3853, 3855, 3856, 3858, 3860, 3861, 3866, 3868, 3872, 3875, 3880, 406220, 444850, 444857, 477601, 477602, 486513, 486518, 486523, 490977, 490978, 490983, 491006, 51350, 697425, 699194, 699320, 699567, 700060, 700449, 702153, 705390, 706830, 707236, 718983, 77055
4° C, store in dark, DO NOT FREEZE!
Liquid
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
AE1/AE3
eFluor 660
KRT13
2310016L08Rik; 3300001P10Rik; 39.1; 40-kDa keratin intermediate filament; 47 kDa cytokeratin; 56 kDa cytokeratin; 57kd keratin; 57kDa keratin; 58 kDa cytokeratin; 60-kDa keratin; 63kDa Keratin; 65 kDa cytokeratin; 67 kDa cytokeratin; AA960620; adult keratin; AI324768; AI528832; AI626930; AI663979; AL022697; alpha keratin; AU019895; AW108092; AW146334; basic epidermal type II cytokeratin (carboxy-terminal region, clone pUF164); BB005427; BCIE; BIE; Card2; cell proliferation-inducing gene 46 protein; CK 2e; CK1; CK-1; CK10; CK-10; CK13; CK-13; CK14; CK-14; CK15; CK-15; CK16; CK-16; CK-17; CK18; CK-18; CK19; CK-19; CK-1B; CK-2e; CK3; CK-3; CK4; CK-4; CK5; CK-5; ck55; CK6A; CK-6A; CK6C; CK-6C; CK6D; CK-6D; CK-6E; CK7; CK-7; CK8; CK-8; CYK18; CYK4; CYK8; CYKER; cytokeratin 1; cytokeratin 10; cytokeratin 13; cytokeratin 14; cytokeratin 15; cytokeratin 16; cytokeratin 18; cytokeratin 19; cytokeratin 3; cytokeratin 4; cytokeratin 5; cytokeratin 6A; cytokeratin 6C; cytokeratin 6D; cytokeratin 7
Mouse
100 μg
Primary
Canine, Human, Mouse, Non-human Primate, Rabbit, Rhesus Monkey
Antibody
IgG1
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