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PAC 1, Tocris Bioscience™

Activator of procaspase-3; pro-apoptotic

Brand:  Tocris (Bio-Techne) 258150

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 50mg

 View more versions of this product

Product Code. 13441514

  • £573.30 / 50mg

Estimated Shipment date
from Supplier 23-10-2019

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Description

Description

Procaspase-activating compound; activates procaspase-3 to produce caspase-3 (EC50 = 0.22 μM). Also activates procaspase-7 in a less efficient manner (EC50 = 4.5 μM). Pro-apoptotic; induces apoptosis in both cancerous and non-cancerous cells dependent on procaspase-3 concentration (IC50 values are 0.003 - 1.41 and 5.02 - 9.98 μM respectively).
Specifications

Chemical Identifiers

315183-21-2
392.503
pac-1, procaspase-3 activator, procaspase activating compound 1, procaspase-3 activator, pac-1, 4-benzylpiperazino acetic acid-3-allyl-2-hydroxybenzylidene hydrazide, 2-4-benzylpiperazin-1-yl-n'-z-6-oxo-5-prop-2-enylcyclohexa-2,4-dien-1-ylidene methyl acetohydrazide, d01yif, e-n'-3-allyl-2-hydroxybenzylidene-2-4-benzylpiperazin-1-yl acetohydrazide, 2-4-benzylpiperazin-1-yl-n'-1e-2-hydroxy-3-prop-2-en-1-yl phenyl methylidene acetohydrazide, 4-phenylmethyl-1-piperazineacetic acid 2-hydroxy-3-2-propenyl phenyl methylene hydrazide
2-(4-benzylpiperazin-1-yl)-N'-[(Z)-(6-oxo-5-prop-2-enylcyclohexa-2,4-dien-1-ylidene)methyl]acetohydrazide
C23H28N4O2
XSGXRYNZNGUGEJ-PGMHBOJBSA-N
6851947
C=CCC1=CC=CC(=CNNC(=O)CN2CCN(CC2)CC3=CC=CC=C3)C1=O

Specifications

50mg
315183-21-2
pac-1, procaspase-3 activator, procaspase activating compound 1, procaspase-3 activator, pac-1, 4-benzylpiperazino acetic acid-3-allyl-2-hydroxybenzylidene hydrazide, 2-4-benzylpiperazin-1-yl-n'-z-6-oxo-5-prop-2-enylcyclohexa-2,4-dien-1-ylidene methyl acetohydrazide, d01yif, e-n'-3-allyl-2-hydroxybenzylidene-2-4-benzylpiperazin-1-yl acetohydrazide, 2-4-benzylpiperazin-1-yl-n'-1e-2-hydroxy-3-prop-2-en-1-yl phenyl methylidene acetohydrazide, 4-phenylmethyl-1-piperazineacetic acid 2-hydroxy-3-2-propenyl phenyl methylene hydrazide
C=CCC1=CC=CC(=CNNC(=O)CN2CCN(CC2)CC3=CC=CC=C3)C1=O
392.503
392.5
PAC 1
C23H28N4O2
XSGXRYNZNGUGEJ-PGMHBOJBSA-N
2-(4-benzylpiperazin-1-yl)-N'-[(Z)-(6-oxo-5-prop-2-enylcyclohexa-2,4-dien-1-ylidene)methyl]acetohydrazide
6851947
>98%
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