Thermo Scientific™ p53, Rabbit Monoclonal Antibody (Clone SP5)

Employ part of a comprehensive antibody portfolio with the Thermo Scientific™ p53, Rabbit Monoclonal Antibody (Clone SP5). Studies show rabbit monoclonal antibodies are more sensitive and specific than other available markers.

Overview
Brand: Thermo Scientific™

Manufacturer Part Number: RM-9105-R1

p53 ¬ĘSP5! 1mL Sample

UNSPSC: 12352203

Code: LD

Additional Details:
Additional Details: Weight: 0.01000kg



Product Code. 12663687

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  • Description and Specification
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Description and Specification

Specification

Antigen p53
Applications Western Blotting
Classification Monoclonal
Clone SP5
Conjugate Unlabeled
Cross Reactivity Human
Format Prediluted
Host Species Rabbit
Immunogen Recombinant human full-length wild type p53 protein
Isotype IgG
Quantity 1mL
Regulatory Status IVD
Research Discipline Cancer and Tumor Biology
Type Primary

p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to mdm2, SV40 T antigen and human papilloma virus E6 protein p53 senses DNA damage and possibly facilitating repair. Mutation involving p53 is found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma.

Host Species: Rabbit

Clone: SP5

Isotype: IgG

Species Reactivity: Human. Others not tested.

Epitope: Not determined

Immunogen: Recombinant human full-length wild type p53 protein

Molecular Weight: 53kDa

Positive Control: MDA-231 cells, Colon CA

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting

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