Epredia™ Lab Vision™ p21^WAF1 Ab-5 Mouse Monoclonal Antibody, 200μg/mL, BSA and azide

Achieve accurate, reproducible results with the Epredia™ p21^WAF1 Ab-5, Mouse Monoclonal Antibody.

Product Code	Brand	Form	Quantity
12621277	Epredia™ MS-387-P	Concentrated	1 mL
12631277	Epredia™ MS-387-P1ABX	Concentrated	100 μL
12651277	Epredia™ MS-387-PABX	Concentrated	200 μL
12641277	Epredia™ MS-387-P1	Concentrated	500 μL
12611277	Epredia™ MS-387-P0	Concentrated	100 μL
12671277	Epredia™ MS-387-R7	Prediluted	7 mL

Description

p21^WAF1/Cip1/Sdi1/Pic1 is a tumor suppressor protein. Expression of p21^WAF1 is induced by wild type, but not mutant, p53 suppressor protein. The p21^WAF1 protein binds to cyclin/CDK complexes and inhibits their kinase activity thereby stopping cell cycle progression. It also binds to PCNA (proliferating cell nuclear antigen) and blocks DNA replication but not the DNA repair process.

Host Species: Mouse

Clone: HZ52

Isotype: IgG1

Species Reactivity: Human, Cow, Mouse, and Rat. Others not known.

Epitope: Not determined

Immunogen: Full-length human recombinant p21 protein

Molecular Weight: 21kDa

Positive Control: Ls174T or Raji cells, Colon CA

Cellular Localization: Nuclear

Recommended for:

• Immunohistochemistry (Formalin/paraffin)
• Immunoprecipitation
• Flow Cytometry

Note:

USA: RUO; Int'l: RUO

Specifications

• Antigen: p21superscriptWAF1superscript Ab-5
• Applications: Immunohistochemistry (Paraffin), Immunoprecipitation
• Conjugate: Unconjugated
• Regulatory Status: RUO
• Target Species: Bovine, Human, Rat
• Isotype: IgG1

• Clone: HZ52
• Classification: Monoclonal
• Host Species: Mouse
• Research Discipline: Cancer and Tumor Biology
• Immunogen: Full length human recombinant p21 protein
• Primary or Secondary: Primary