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P-Cadherin Mouse anti-Human, APC, Clone: CSTEM29, eBioscience™

Mouse Monoclonal Antibody

Brand:  Invitrogen 17-2237-42

Additional Details : Weight : 0.01000kg

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Product Code. 15865353

  • £267.00 / Pack of 100
Estimated Shipment: 22-12-2021

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Description

Description

This monoclonal antibody CSTEM29 reacts with human P-Cadherin, also known as Cadherin-3. Applications Reported: This CSTEM29 antibody has been reported for use in flow cytometric analysis. Applications Tested: This CSTEM29 antibody has been pre-diluted and tested by flow cytometric analysis of normal human induced pluripotent stem cells. This may be used at 5 μL (0.25 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Excitation: 633-647 nm; Emission: 660 nm; Laser: Red Laser. Filtration: 0.2 μm post-manufacturing filtered.

P-cadherin, also known as Cadherin-3, is a Type 1 cadherin protein that belongs to the cadherin superfamily. Type 1 cadherins are single-pass transmembrane proteins that have 5 extracellular cadherin repeats and an intracellular domain that binds p120-catenin and beta-catenin. Cadherins are calcium-dependent cell-cell adhesion glycoproteins responsible for a range of processes including development, wound healing, cell-cell signaling, cell growth and differentiation. P-cadherin is expressed in human fetal structures, and in adult tissues such as the basal layer of the epidermis, breast, prostate, ovary, cervix, hair follicle, and corneal endothelium. P-cadherin expression has also been reported on embryonic stem cells, and stem cells of the normal mammary gland, and hair follicle. Overexpression of P-cadherin has been associated with poor prognosis in breast, prostate, ovary, colon, and stomach carcinomas. Mutations in CDH3 are associated with congential hypotrichosis with juvenile macular dystrophy.
Specifications

Specifications

P-Cadherin
Monoclonal
5 μL/Test
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
P22223
Cadherin-3, CDH3, PCAD
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry
CSTEM29
APC
CDH3
Liquid
CDH3
IgG2a, kappa
100 Tests
4° C, store in dark, DO NOT FREEZE!
Primary
1001
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