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Osteopontin Mouse anti-Human, eFluor 660, Clone: 2F10, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 50-9096-42

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15520077

  • £182.82 / 100 tests


Estimated Shipment date
from Supplier 01-09-2017
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Disclaimers:

For Research Use Only.


Specifications

Description

The 2F10 monoclonal antibody recognizes human osteopontin (OPN), a secreted glycophosphoprotein expressed by multiple cell types, including leukocytes, fibroblasts, dendritic cells, macrophages, myoblasts, bone-forming cells, and epithelial cells. OPN is an extracellular matrix protein with multiple roles, including bone resorption and calcification, immune system regulation, wound healing, and tumorigenesis. Thrombin cleavage of OPN allows binding of integrin receptors, expressed by immune cells, and subsequent modulation of cell adhesion, migration, and survival. OPN is expressed in bones, teeth, placenta, blood vessels, kidney, and various tumors. Osteopontin has been identified as a potential therapeutic target in the treatment of autoimmune disease, cancer metastasis, bone mineralization diseases, and osteoporosis.
Description & Specifications

Specifications

Osteopontin
2F10
eFluor 660
Conjugated
Murine
100 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry
5μL (0.25μg)/test
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
bone sialoprotein I (BSP-1)
IgG1
RUO
Primary
Human