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Oncrasin 1, Tocris Bioscience™

Induces abnormal nuclear aggregation of PKCι; proapoptotic

Brand:  Tocris (Bio-Techne) 342750

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 50mg

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Product Code. 13432994

  • £399.84 / 50mg

Estimated Shipment date
from Supplier 01-04-2020

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Description

Description

Proapoptotic agent that induces abnormal nuclear aggregation of PKCι and suppresses RNA transcription. Exhibits antiproliferative effects against various human tumor cell lines with K-Ras mutations (IC50 ≤ 3 μM) with minimal effects on normal epithelial cells and inhibits human xenograft growth by 75% in vivo.
Specifications

Chemical Identifiers

75629-57-1
269.728
oncrasin-1, 1-4-chlorobenzyl-1h-indole-3-carbaldehyde, oncrasin 1, 1-4-chlorophenyl methyl indole-3-carbaldehyde, 1-4-chlorophenyl methyl-1h-indole-3-carboxaldehyde, 1-4-chloro-benzyl-1h-indole-3-carbaldehyde, oncrasin1, cambridge id 5601604, n-4-chlorobenzyl-3-formylindole, oncrasin hplc
1-[(4-chlorophenyl)methyl]indole-3-carbaldehyde
C16H12ClNO
ZDRQMXCSSAPUMM-UHFFFAOYSA-N
872445
C1=CC=C2C(=C1)C(=CN2CC3=CC=C(C=C3)Cl)C=O

Specifications

50mg
75629-57-1
oncrasin-1, 1-4-chlorobenzyl-1h-indole-3-carbaldehyde, oncrasin 1, 1-4-chlorophenyl methyl indole-3-carbaldehyde, 1-4-chlorophenyl methyl-1h-indole-3-carboxaldehyde, 1-4-chloro-benzyl-1h-indole-3-carbaldehyde, oncrasin1, cambridge id 5601604, n-4-chlorobenzyl-3-formylindole, oncrasin hplc
C1=CC=C2C(=C1)C(=CN2CC3=CC=C(C=C3)Cl)C=O
269.728
269.73
Oncrasin 1
C16H12ClNO
ZDRQMXCSSAPUMM-UHFFFAOYSA-N
1-[(4-chlorophenyl)methyl]indole-3-carbaldehyde
872445
>98%
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