Oncostatin M Receptor Mouse anti-Human, PE, Clone: AN-V2, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 12-1303-41

Product Code. 15546876

Disclaimers:

For Research Use Only.

Description

This monoclonal AN-V2 antibody reacts with the human oncostatin M (OSM) receptor. OSM, which belongs to the interleukin-6 cytokine family, is produced by T cells, activated monocytes, and dendritic cells. In humans, OSM can bind two unique receptor complexes. The type I OSM receptor is composed of the LIFR associated with gp130, and recognizes both LIF and OSM. The type II OSM receptor, which consists of gp130 and the OSMR subunit, specifically binds the cytokine, leading to activation of the JAK/STAT signaling pathway. Reports have also indicated a soluble form of the OSM receptor, which this antibody also recognizes. The OSM receptor is expressed in the bone marrow, endothelium, liver, lung, and numerous tumor cell lines.

The AN-V2 monoclonal antibody recognizes the type II (beta) OSM receptor.

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Specifications

• Antigen: Oncostatin M Receptor
• Clone: AN-V2
• Conjugate: PE
• Format: Conjugated
• Host Species: Murine
• Quantity: 25 Tests
• Storage Requirements: Store at 2-8°C. Do not freeze. Light-sensitive material.
• Monoclonal or Polyclonal: Monoclonal

• Applications: Flow Cytometry
• Concentration: 5μL (0.5μg)/test
• Formulation: aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
• Gene Alias: OSMR
• Isotype: IgG1
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Human