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NVP DPP 728 dihydrochloride, Tocris Bioscience™

Potent, orally active dipeptidyl peptidase IV (DPP-IV) inhibitor

Brand:  Tocris (Bio-Techne) 350610

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 10mg

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Product Code. 13463094

  • £183.48 / 10mg


Estimated Shipment
04-10-2018
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Description

Description

Potent, orally active dipeptidyl peptidase (DPP)-IV inhibitor (Ki = 11 nM, IC50 = 14 nM) that displays > 15 000-fold selectivity over DPP-II and a range of proline-cleaving proteases. Exhibits antidiabetic activity in vivo; improves glucose tolerance, increases glucagon-like peptide 1 (GLP-1) and insulin levels, augments insulin secretion and GLUT2 levels, and reduces (preserves) islet size.
Specifications

Chemical Identifiers

207556-62-5
371.266
6-[[2-[[2-(2S)-2-Cyano-1-pyrrolidinyl]-2-oxoethyl]amino]ethyl]amino-3-pyridinecarbononitrile dihydrochloride
C15H20Cl2N6O
VNACOBVZDCLAEV-GXKRWWSZSA-N
9799555

Specifications

NVP DPP 728 dihydrochloride
207556-62-5
C15H20Cl2N6O
VNACOBVZDCLAEV-GXKRWWSZSA-N
6-[2-[[2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl]amino]ethylamino]pyridine-3-carbonitrile;dihydrochloride
9799555
10mg
>98%
6-[[2-[[2-(2S)-2-Cyano-1-pyrrolidinyl]-2-oxoethyl]amino]ethyl]amino-3-pyridinecarbononitrile dihydrochloride
C1CC(N(C1)C(=O)CNCCNC2=NC=C(C=C2)C#N)C#N.Cl.Cl
371.266
371.27
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