Nur77 Mouse anti-Mouse, PerCP-eFluor 710, Clone: 12.14, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 46-5965-80

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Disclaimers: For Research Use Only.

Product Code. 15509326

Quantity Price
1 £ 84.99 / 25µg
EU Stock 1
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Description and Specification

Specification

Primary or Secondary Primary
Concentration 0.2mg/mL
Species Reactivity Mouse
Clone 12.14
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Regulatory Status RUO
Gene Alias NGFI-B, NR4A1, TR3, NAK1
Applications Flow Cytometry (Intracellular Staining)
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
Conjugate PerCP-eFluor 710
Format Conjugated
Quantity 25μg
Monoclonal or Polyclonal Monoclonal
Antigen Nur77
Isotype IgG1
Host Species Mouse

This 12.14 monoclonal antibody reacts with mouse Nur77 (also known as NR4A1, TR3, NGFI-B, or NAK1), an inducible orphan nuclear receptor. Expressed in thymocytes and T cell lines, Nur77 promotes apoptosis and plays a role in thymocyte negative selection. Additionally, Nur77 has been shown to be critical for steroid biosynthesis in Leydig cells as well as for the effects of dopamine. In addition, Nur77 has been shown to interact with FoxP3 in regulatory T cells. However, our results with this antibody do not correlate with this observation.