Nur77 Mouse anti-Mouse, PE, Clone: 12.14, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 12-5965-80

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15298939

Quantity Price
1 £ 67.24 / 25µg
EU Stock 5
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Description and Specification

Specification

Regulatory Status RUO
Applications Flow Cytometry (Intracellular Staining)
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Quantity 25μg
Format Conjugated
Monoclonal or Polyclonal Monoclonal
Gene Alias NGFI-B, NR4A1, TR3, NAK1
Antigen Nur77
Host Species Mouse
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Clone 12.14
Species Reactivity Mouse
Primary or Secondary Primary
Concentration 0.2mg/mL
Isotype IgG1
Conjugate PE

This 12.14 monoclonal antibody reacts with mouse Nur77 (also known as NR4A1, TR3, NGFI-B, or NAK1), an inducible orphan nuclear receptor. Expressed in thymocytes and T cell lines, Nur77 promotes apoptosis and plays a role in thymocyte negative selection. Additionally, Nur77 has been shown to be critical for steroid biosynthesis in Leydig cells as well as for the effects of dopamine. In addition, Nur77 has been shown to interact with FoxP3 in regulatory T cells. However, our results with this antibody do not correlate with this observation.